Paired Associates Learning Task

HED Task ID: hedtsk_paired_associates_learning

Also known as: PAL, Paired Associate Learning

Study of cue-target pairs followed by cued recall; proportion recalled indexes associative encoding and retrieval.

Description

Participants learn arbitrary associations between stimuli and their locations (or between word pairs). In a typical computerized version (CANTAB PAL), abstract patterns appear in boxes around the screen during the study phase, and during test, patterns are presented centrally and participants must identify the correct box location. Difficulty increases across stages from 1-2 to 6-8 pairs. Performance is measured by patterns correctly learned and errors made. The PAL task is particularly sensitive to hippocampal function and shows early sensitivity to amyloid-beta pathology in preclinical Alzheimer’s disease.

Inclusion test

Procedure

Participants study pairs of items (word-word, face-name, object-location) and are later cued with one member to recall the other.

Manipulation

Pair relatedness (semantic, unrelated); number of pairs; study-test cycles; cue type.

Measurement

Cued recall accuracy; number of cycles to criterion; intrusion errors.

Variations

Variation

Description

Justification

Verbal Paired Associates (Cued Recall)

Word pairs; cue with first word, recall second.

Canonical word-word pairs with cued recall test

Face-Name Paired Associates

Naturalistic variant; sensitive to aging and early AD.

Face-name binding; social memory domain

Object-Location Pairs

Associate objects with spatial locations; engages hippocampal binding.

Object-location binding; spatial memory component

CANTAB PAL

Computerized abstract pattern-location associations; graded difficulty.

Touchscreen object-location paradigm; named computerized instrument

Arbitrary vs. Semantically Related Pairs

Unrelated pairs tax hippocampal binding; related pairs benefit from semantic support.

Relatedness manipulation changes encoding strategy

Cross-Modal Paired Associates

Pair across modalities (sound-image, word-location).

Pairs span sensory modalities; cross-modal binding demand

Multi-Trial Learning Curves

Repeated study-test cycles; tracks acquisition rate.

Repeated study-test cycles; tests learning rate over trials

Retroactive/Proactive Interference Variants

Overlapping pairs (A-B, A-C) to study interference mechanisms.

Competing pairs introduced; tests interference in associative memory

Incidental vs. Intentional Encoding

With or without awareness of upcoming test.

Encoding goal manipulation; tests depth and intentionality of encoding

Cognitive processes

This task engages the following cognitive processes:

Key references

  • {‘authors’: ‘de Rover, M., Pironti, V. A., McCabe, J. A., Acosta-Cabronero, J., Arana, F. S., Morein-Zamir, S., Hodges, J. R., Robbins, T. W., Fletcher, P. C., Nestor, P. J., & Sahakian, B. J.’, ‘year’: 2011, ‘title’: ‘Hippocampal dysfunction in patients with mild cognitive impairment: A functional neuroimaging study of a visuospatial paired associates learning task’, ‘venue’: ‘Neuropsychologia’, ‘venue_type’: ‘journal’, ‘journal’: ‘Neuropsychologia’, ‘volume’: ‘49’, ‘issue’: ‘7’, ‘pages’: ‘2060-2070’, ‘doi’: ‘10.1016/j.neuropsychologia.2011.03.037’, ‘openalex_id’: None, ‘pmid’: None, ‘citation_string’: ‘de Rover, M., Pironti, V. A., McCabe, J. A., et al. (2011). Hippocampal dysfunction in patients with mild cognitive impairment: A functional neuroimaging study of a visuospatial paired associates learning task. Neuropsychologia, 49(7), 2060-2070.’, ‘url’: ‘https://doi.org/10.1016/j.neuropsychologia.2011.03.037’, ‘source’: ‘crossref’, ‘confidence’: ‘high’, ‘verified_on’: ‘2026-04-20’}

Recent references

  • {‘authors’: ‘Atkinson, A. L., Berry, E. D., Waterman, A. H., Baddeley, A. D., Hitch, G. J., & Allen, R. J.’, ‘year’: 2018, ‘title’: ‘Are there multiple ways to direct attention in working memory?’, ‘venue’: ‘Annals of the New York Academy of Sciences’, ‘venue_type’: ‘journal’, ‘journal’: ‘Annals of the New York Academy of Sciences’, ‘volume’: ‘1424’, ‘issue’: ‘1’, ‘pages’: ‘115-126’, ‘doi’: ‘10.1111/nyas.13634’, ‘openalex_id’: None, ‘pmid’: None, ‘citation_string’: ‘Atkinson, A. L., Berry, E. D. J., Waterman, A. H., Baddeley, A. D., Hitch, G. J., & Allen, R. J. (2018). Are there multiple ways to direct attention in working memory? Annals of the New York Academy of Sciences, 1424(1), 115–126.’, ‘url’: ‘https://doi.org/10.1111/nyas.13634’, ‘source’: ‘crossref’, ‘confidence’: ‘high’, ‘verified_on’: ‘2026-04-20’}

  • {‘authors’: ‘Lim, S., Fiez, J. A., & Holt, L. L.’, ‘year’: 2014, ‘title’: ‘How may the basal ganglia contribute to auditory categorization and speech perception?’, ‘venue’: ‘Frontiers in Neuroscience’, ‘venue_type’: ‘journal’, ‘journal’: ‘Frontiers in Neuroscience’, ‘volume’: ‘8’, ‘issue’: None, ‘pages’: None, ‘doi’: ‘10.3389/fnins.2014.00230’, ‘openalex_id’: None, ‘pmid’: None, ‘citation_string’: ‘Lim, S. J., Fiez, J. A., & Holt, L. L. (2014). How may the basal ganglia contribute to auditory categorization and speech perception? Frontiers in Neuroscience, 8, 230.’, ‘url’: ‘https://doi.org/10.3389/fnins.2014.00230’, ‘source’: ‘crossref’, ‘confidence’: ‘high’, ‘verified_on’: ‘2026-04-20’}

  • {‘authors’: ‘Parra, M. A., Abrahams, S., Logie, R. H., Méndez, L. G., Lopera, F., & Della Sala, S.’, ‘year’: 2010, ‘title’: ‘Visual short-term memory binding deficits in familial Alzheimer’s disease’, ‘venue’: ‘Brain’, ‘venue_type’: ‘journal’, ‘journal’: ‘Brain’, ‘volume’: ‘133’, ‘issue’: ‘9’, ‘pages’: ‘2702-2713’, ‘doi’: ‘10.1093/brain/awq148’, ‘openalex_id’: None, ‘pmid’: None, ‘citation_string’: “Parra, M. A., Abrahams, S., Logie, R. H., Méndez, L. G., Lopera, F., & Della Sala, S. (2010). Visual short-term memory binding deficits in familial Alzheimer’s disease. Brain, 133(9), 2702–2713.”, ‘url’: ‘https://doi.org/10.1093/brain/awq148’, ‘source’: ‘crossref’, ‘confidence’: ‘high’, ‘verified_on’: ‘2026-04-20’}

  • {‘authors’: ‘Naveh-Benjamin, M.’, ‘year’: 2000, ‘title’: ‘Adult age differences in memory performance: Tests of an associative deficit hypothesis.’, ‘venue’: ‘Journal of Experimental Psychology: Learning, Memory, and Cognition’, ‘venue_type’: ‘journal’, ‘journal’: ‘Journal of Experimental Psychology: Learning, Memory, and Cognition’, ‘volume’: ‘26’, ‘issue’: ‘5’, ‘pages’: ‘1170-1187’, ‘doi’: ‘10.1037/0278-7393.26.5.1170’, ‘openalex_id’: None, ‘pmid’: None, ‘citation_string’: ‘Naveh-Benjamin, M. (2000). Adult age differences in memory performance: Tests of an associative deficit hypothesis. Journal of Experimental Psychology: Learning, Memory, and Cognition, 26(5), 1170–1187. [Updated: Old, S. R., & Naveh-Benjamin, M. (2008). Differential effects of age on item and associative measures of memory. Psychology and Aging, 23(1), 104–118.]’, ‘url’: ‘https://doi.org/10.1037/0278-7393.26.5.1170’, ‘source’: ‘crossref’, ‘confidence’: ‘high’, ‘verified_on’: ‘2026-04-20’}